Twenty One Hotel

  • Free WiFi
  • Low Deposit Options Available
  • Interest FREE Payment Plans
TripAdvisor Traveller rating:
1399 reviews

Located on Via Cola di Rienzo, the hotel is situated in the elegant Prati district, home to the Vatican and Saint Peter's Basilica. Vatican City can be reached in around 15 minutes ... Continue reading

Located on Via Cola di Rienzo, the hotel is situated in the elegant Prati district, home to the Vatican and Saint Peter's Basilica. Vatican City can be reached in around 15 minutes on foot and Piazza del Popolo and Piazza di Spagna are also within walking distance. The hotel is a charming modern boutique hotel with 86 rooms. Guests are welcomed in the lobby with 24-hour reception, 24-hour check-out service and a hotel safe. A bar and restaurant are also available. The hotel also offers a laundry service and garage parking facilities. The en suite rooms are elegant and feature attention to detail. A continental breakfast buffet is available in the bright breakfast room. The Wine Bar serves the best champagne and summates wines.


  • Air conditioning
  • Designated smoking area
  • Facilities for disabled guests
  • Family rooms
  • Free WiFi
  • Heating
  • Lift
  • Newspapers
  • Non smoking rooms
  • Room service
  • Safety deposit box
  • Shared lounge/TV area
  • Shuttle service (surcharge)
  • Soundproof rooms

Price Overview

The prices shown below show the cheapest holiday offers for the Twenty One Hotel in Rome. Please use the price links to see all holiday deals available for that month.

Price Overview 2016 2017
Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep
Holidays from - - - - - - - - - - - -
Avg. Daily Temp (°C) 23 17 13 13 14 17 19 24 29 32 32 27
Avg. Evening Temp (°C) 12 8 4 3 3 6 8 13 17 19 19 16

Payment Options

Payment options accepted:

We do not charge a fee to our customers who use debit cards, but credit cards do incur a fee of 2.5% of the payment value.

To make booking a holiday at Twenty One Hotel in Rome easier for you, we provide a range of different payment options. To find out if you can book Twenty One Hotel with a low deposit holiday option, please click the "Price and Availability" button above.

Essential Information

Time Zone

Plug Type

Voltage 220V 50Hz
Language: Italian,
Currency: Euro (€)
€1 = £0.81

This week's weather forecast

27°C Low 17°C
Today: Tue 25 Oct
Partly cloudy
27°C Low 17°C
Wed 26 Oct
25°C Low 11°C
Thu 27 Oct
24°C Low 10°C
Fri 28 Oct
24°C Low 10°C
Sat 29 Oct

Photos of the Rome area

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Photos provided by Panoramio. Photos are under the copyright of their owners.

Questions and Answers about Twenty One Hotel

If you can’t find what you’re looking for or if you have a question about this specific hotel, please get in touch via the Add a Question button below. Our knowledgeable team will aim to respond to your question within 72 hours. In the meantime, previously asked questions can be found below and answers to some of the most commonly asked questions can be found on our FAQs page.

1 Questions | 2 Answers

Some of the rooms have a balcony , just make sure that you select the room with a balcony

Added 6 months ago.

By Sally.Dademo, team member

Rate Answer:

Hello, Not all rooms at this hotel feature a balcony. We would advise you to add a special request to your booking for a balcony. Regards

Added 6 months ago.

By Leanne, team member

Rate Answer:



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